この項目では、鎮咳去痰薬について説明しています。ロックバンドについては「コデイン (バンド)」をご覧ください。
The mixture of promethazine hydrochloride and codeine phosphate iscontraindicated in pediatric people below 6 many years of age.
These persons convert codeine into its Lively metabolite, morphine, a lot more rapidly and completely than Other individuals. This fast conversion-results in greater than predicted serum morphine ranges. Even at labeled dosage regimens, people who are extremely-fast metabolizers could have life-threatening or lethal respiratory despair or knowledge indications of overdose (for example extreme sleepiness, confusion, or shallow respiratory). (See OVERDOSAGE). Kids with obstructive rest apnea who're addressed with codeine for article-tonsillectomy and/or adenoidectomy pain might be specially sensitive to the respiratory depressant effects of codeine that has been quickly metabolized to morphine. Codeine is contraindicated for publish-operative soreness management in all pediatric sufferers undergoing tonsillectomy and/or adenoidectomy. (See CONTRAINDICATIONS). When prescribing codeine-containing medicines, Health care companies need to select the cheapest powerful dose to the shortest period of time and advise clients and caregivers about these pitfalls plus the signs of morphine overdose.
This is named adrenal insufficiency. Adrenal insufficiency can worsen if Your whole body is beneath strain thanks to fever, medical procedures, or trauma. Notify your healthcare service provider if you have any of the following symptoms of adrenal insufficiency.
Decrease Seizure Threshold – Promethazine may decrease seizure threshold. It ought to be utilised with caution in individuals with seizure disorders or in individuals who're making use of concomitant remedies, including narcotics or community anesthetics, which may also have an impact on seizure threshold.
We proudly offer necessary Girls’s overall health treatment products for reproductive well being. Regardless of whether you happen to be in search of medication for beginning Manage, taking care of menopause indications, or making sure your reproductive overall health, our range delivers responsible and Safe and sound solutions.
Antihistamines and codeine are equally contraindicated for use inside the treatment method of lessen respiratory tract signs, including asthma.
The next laboratory checks can be influenced in sufferers who're receiving therapy with promethazine hydrochloride.
Naloxone is often a drugs that can quickly reverse the consequences of the opioid overdose. The Australian Government is providing this medication totally free click here and and not using a prescription to people who might practical experience, or witness, an opioid overdose.
Promethazine/phenylephrine/codeine might also be employed for other situations as determined by your Health care company.
We also determined nine situations of serious respiratory difficulties, including 3 deaths, with using tramadol in little ones more youthful than eighteen yrs from January 1969 to March 2016 (see Info Summary). The majority of critical Unwanted effects with each codeine and tramadol transpired in small children younger than 12 several years, and several conditions occurred right after one dose of the medicine.
Allergies to Elements. People who are allergic to any of the subsequent shouldn't get promethazine/phenylephrine/codeine.
Test along with your health practitioner or hospital emergency area straight away In case your newborn reveals indications of increased sleepiness (a lot more than regular), issue breastfeeding, issue respiratory, or limpness. These may be signs and symptoms of an overdose and want instant healthcare focus.
** P.c Everyday Value relies over a 2000 calorie food plan. Your every day values might be better or decrease based on your calorie demands.